Etomidate is a go-to induction agent in neuro anesthesia for a reason: predictable hypnosis via GABA-A receptor facilitation, decreased CMRO₂, CBF, and ICP, and excellent hemodynamic stability that helps preserve cerebral perfusion pressure. Just remember its effects on somatosensory-evoked potentials—both amplitude and latency can increase, which matters when neuromonitoring is in play. References: Barash Clinical Anesthesia, 7th Edition, pp. 489–490 Miller’s Anesthesia, 8th Edition, pp. 851–85
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Etomidate is a go-to induction agent in neuro anesthesia for a reason: predictable hypnosis via GABA-A receptor facilitation, decreased CMRO₂, CBF, and ICP, and excellent hemodynamic stability that helps preserve cerebral perfusion pressure. Just remember its effects on somatosensory-evoked potentials—both amplitude and latency can increase, which matters when neuromonitoring is in play. References: Barash Clinical Anesthesia, 7th Edition, pp. 489–490 Miller’s Anesthesia, 8th Edition, pp. 851–85
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Every anesthesia resident gets asked this question sooner or later: What’s the BEST induction agent? The truth? It depends on the patient. 💉 Etomidate – rapid onset and very hemodynamically stable, but concerns exist about adrenal suppression, especially in septic patients. 💉 Ketamine – increasingly popular in critically ill patients because it supports blood pressure with its sympathomimetic effects and does not suppress adrenal function. 💉 Propofol – the classic OR induction drug, smooth an
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Etomidate specifically targets a receptor in the brain called the GABA-A receptor. This receptor normally helps to calm the brain’s activity. When etomidate binds to this receptor, it enhances the receptor’s calming effect, which leads to sedation and anesthesia. ⁣ ⁣ ❗️Need more medication help?! Check out our ER Med Cheat Sheet on RNNewGrads.com to have the most important information on over 60 of the most common medications in the ER at your fingertips❗️ | rnnewgrads
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