An international team of researchers recently concluded that men with primary biliary cholangitis (PBC) have more-severe progression of their disease—with worse outcomes—compared to women with PBC. In ...

The cholangitis infection is often caused by bacteria, a gallstone or any another blockage. Primary biliary cholangitis is a chronic condition where inflammation of the bile duct system keeps bile ...

Unbearable itching, crushing fatigue and years on “standby” waiting for a liver transplant became this 43-year-old divemaster’s reality after she was diagnosed with primary biliary cholangitis – a ...

Seladelpar is an oral, selective peroxisome proliferator-activated receptor delta agonist. Treatment with seladelpar was associated with an improvement in cholestatis markers in patients with primary ...

S ince there’s no cure for primary biliary cholangitis (PBC), the main treatment goal is to slow disease progression and ease symptoms, such as itching. The good news is that, for most people, the ...

In 2016, obeticholic acid became the first new licensed therapy for primary biliary cholangitis in >20 years. This therapeutic came at a time of improved disease understanding from biliary and ...

The treatment is expected to reprogram the immune system to induce tolerance to PDC-E2. The Food and Drug Administration (FDA) has granted Fast Track designation to CNP-104 for the treatment of ...

Please provide your email address to receive an email when new articles are posted on . A greater percentage of patients treated with seladelpar achieved biochemical response and normalization of ...

WASHINGTON, DC — Measures of liver stiffness remained stable or improved in patients with primary biliary cholangitis (PBC) after 36 months of treatment with seladelpar (Livdelzi) based on new data ...

It is unclear what role treatment plays in affecting hepatocellular carcinoma (HCC) risk, the authors found. The authors wrote about the latest evidence related to the risks and outcomes of HCC in ...

While PBC progresses slowly and many patients do not experience symptoms during the early stages of disease, there are many symptoms to look out for. In later stages of disease, patients may ...