Higgins is an advocate for people with Li-Fraumeni syndrome. I was born with an inherited cancer syndrome, Li-Fraumeni syndrome (LFS). A mutation on my Tp53 cancer suppressor gene makes me susceptible ...

After Sarah Holm, then 40, found a lump in her breast, she was diagnosed with two different types of breast cancer. As she grappled with cancer treatments, her son, Jack, 11, started complaining of ...

In a prospective validation study, researchers at The University of Texas MD Anderson Cancer Center have demonstrated that a new mathematical model called LFSPRO was effective in supporting genetic ...

Li-Fraumeni syndrome (LFS) raises the risk of getting many types of cancer. LFS happens as a result of changes (also called mutations or variants) in the TP53 gene. LFS-related cancers often happen ...

We conducted a retrospective cohort study at The University of Utah and University of Wisconsin-Madison. Cancer genetics registries were reviewed to identify all unrelated families with LFS seen ...

An estimated 170,000 Australians were diagnosed with cancer in 2025. Many people know the causes of cancer are partly genetic. But how do your genes, which contribute so much of what makes you you, ...

“In med school, doctors are taught ‘when you hear hoof beats, think horse, not zebra,’” says Jenny Gray. “But in our case, we’re unicorns.” In Jenny’s case, her mother and maternal grandfather were ...

Erica Shemwell is carrying a heavy weight. The star of the new TLC series The Blended Bunch already lost her first husband, Tony, to brain cancer. And in the March 30 episode of the reality show, she ...

A new risk model proves to be effective at identifying the risk for a rare genetic condition that increases predisposition for cancer.

In a prospective validation study, researchers at The University of Texas MD Anderson Cancer Center demonstrated that a new mathematical model, called LFSPRO, was effective in supporting genetic ...

In a study published in Cancer Discovery, researchers from Canada tested the use of a multimodal liquid biopsy assay based on cell-free DNA (cfDNA) for early cancer detection in patients with ...