Researchers have solved the the structure of the complex formed when mRNA is being scanned to find the starting point for translating RNA into a protein. The discovery provides a new understanding of ...

No-go decay (NGD) is a mRNA quality-control mechanism in eukaryotic cells that leads to degradation of mRNAs stalled during translational elongation. The key factors triggering NGD are Dom34 and Hbs1.

The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...

Researchers from Tokyo Metropolitan University and RIKEN CSRS have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the ...

Intracellular pathogens are responsible for an enormous amount of worldwide morbidity and mortality, and each has evolved specialized strategies to establish and maintain their replicative niche.

Scientists call them toxins. But these bacterial proteins don't poison us, at least not directly. Instead, they restrain the growth of the bacteria that make them, establishing a dormant "persister ...