The signal recognition particle (SRP) co-translationally targets proteins to the endoplasmic reticulum in eurkaryotes or to the plasma membrane in prokaryotes. As the initiating step, SRP binds to the ...
The signal recognition particle (SRP) recognizes and binds the signal sequence of nascent proteins as they emerge from the ribosome. We present here the 3.0-Å structure of a signal sequence bound to ...