Epigenetics, the modification of chromosomes without altering DNA sequences, serves as a crucial regulatory mechanism for gene expression. Among the various epigenetic marks, N6-methyladenosine (m6A) ...

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs). As the most abundant internal modification of ...

STORM Therapeutics Ltd. (STORM), the clinical stage company pioneering cellular reprogramming through RNA modifications to treat disease, today announced a strategic collaboration with Alida ...

RNA molecules can be modified by enzymes through the addition or removal of chemical groups, but the roles of these modifications in the regulation of both mRNAs and non-coding RNAs are not fully ...

At the onset of diabetic cardiomyopathy, Trdn-as expression increases, which regulates the methylation of Casq2 mRNA mediated by METTL14, thus increasing the stability and expression of Casq2 mRNA.