Just as a misshapen key can't open a lock, the proteins in our cells need to have the correct 3D shape to function properly. And defects in a protein's structure can cause diseases. Proteins are ...
Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature. Ribosomes, the cell's dedicated molecular machines ...
The chaperonin system is pivotal in maintaining cellular proteostasis through its ATP-dependent mediation of protein folding. Among these, the TRiC/CCT complex has emerged as a key molecular machine ...
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