Osteoblasts derived from MSCs are cells required for bone formation. Oxidative phosphorylation produces a lot of ATP and other products including NAD+ and ROS. These factors play important roles in ...

Hypertrophic chondrocytes are deeply involved in the growth of mammalian bones. Researchers find that these cells transform into multiple functional cell types, including those responsible for ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

A research team from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine at the University of ...

Am J Health Syst Pharm. 2006;63(5):419-430. During resorption, growth factors and proteins released from osteoblast precursors and bone stimulate the differentiation, chemotaxis, and proliferation of ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling-aa ...

Osteoporosis or the weakening of bones makes the aging population vulnerable to fractures and a decreased quality of life. The parathyroid hormone (PTH)-derived peptide -- teriparatide has ...

For those suffering from primary bone cancer — which is cancer that originates in the bones — a promising new medication may be on the horizon. The drug, called CADD522, works by blocking a gene ...

Studies by University of Birmingham researchers suggest that a naturally occurring peptide known as PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration), could represent a promising potential ...