Hosokawa Micron partnered with one of the largest pharmaceutical companies globally to develop a novel Contained Particle Size Reduction Facility to realize flexible milling down to superfine ...

Conventional DLS instruments use a detection angle of 90°. The concentration limit of instruments using such optics is very low, as multiple scattering effects need to be eliminated. Multiple ...

The authors evaluate the effect of various mill types on particle-size distribution, flowability, tabletability, and compactibility. The particle-size distribution of a pharmaceutical granulation is ...

Dr Michael Caves, India Business Development Manager, Malvern Instruments, in this article looks at how milling can be automated using real-time particle size measurement, and examines the potential ...

Starting up a new process typically involves a series of iterative changes to process settings until the particle size (blue line) is within the required specification (dotted orange lines). Figure 1.

Wet bead milling is used to produce nanoparticle suspensions at industrial scales. Continuous monitoring of particle size during comminution would allow real-time end-point determination and critical ...

Without a sieve or a mill, pharmaceutical tablet manufacture is almost impossible. These are required whenever active and inactive materials are handled, when tablets or other products are made.

The pharmaceutical manufacturing platforms of fluid-bed granulation and milling are widely used to modify particle size. However, the adoption of process analytical technology to monitor and control ...