In this review we provide an overview of the roles of Hsp70 in cancer, spanning the initial observations that the levels of the heat shock protein Hsp70 are elevated in many human tumors, to ...
p53 is a protein widely recognized for its importance in the human tumor development suppression (Vousden and Lane, 2007), but from a biophysical point of view an isolated p53 is known for its ...
Stress or heat shock proteins (HSPs) such as HSP70 are expressed in response to a wide variety of physiological and environmental insults including heat, reactive oxygen species or anticancer drugs.