With laboratory methods and diagnostics advancing apace, Francesca Lake considers whether PCR is likely to retain its crown as an essential lab method, or whether it could be replaced and consigned to ...

A team of UK-based scientists has recently developed an allele-specific probe polymerase chain reaction method that can accurately detect different variants/lineages of severe acute respiratory ...

As food safety laboratories strive for faster, reliable, and audit-ready pathogen detection, success depends on more than ...

Malaria is a widespread infectious disease characterized by a wide spectrum of clinical manifestations, ranging from asymptomatic carriers to severe acute infections 1. According to the World Health ...

Current antiretroviral therapies (ART), when taken daily, suppress viral loads of human immunodeficiency virus 1 infections (HIV-1) such that ongoing viral transmission is halted 1,2,3. A variety of ...

Definition: DNA amplification is the laboratory process of making many copies of a selected DNA sequence from a very small starting amount. It allows DNA that would otherwise be too scarce to detect ...

Digital PCR, or dPCR, is a molecular biology technique that detects and quantifies nucleic acid targets. By partitioning a sample into many individual reactions, scientists can measure whether a ...

PCR genetic analysis has been in the spotlight since COVID-19, but light is now further facilitating PCR-free methods. Osaka Metropolitan University scientists have developed a light-induced DNA ...

PCR is a technique used to amplify target DNA in a sample. It’s a well-known method that has undergone numerous modifications to enhance its capabilities. This year, it’s turning 40 years old. PCR has ...

Currently established rapid methods for sterility testing of advanced therapy medicinal products (ATMPs) are mostly based on growth-based processes or the detection of metabolic activities. However, ...

Researchers have developed a light-induced DNA detection method that enables rapid, PCR-free genetic analysis. Their technique offers ultra-sensitive mutation detection in just five minutes, reducing ...