Drug overdose deaths, once rare, are now the leading cause of accidental death in the U.S., surpassing peak annual deaths caused by motor vehicle accidents, guns and HIV infection. As a former public ...

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April 5, 2012 — Opioid rotation — switching from one opioid drug or route of administration to another to improve the outcome — is largely to blame for the growing number of unintentional deaths ...

The Annals of Pharmacotherapy. 2006;40(7):1327-1335. The classification of opioid analgesics may be based on 3 different schemes: (1) analog class (phenanthrene, phenylpiperidine, diphenylheptane), (2 ...