Normal phase HPLC is a valuable technique for the separation of polar and hydrophilic compounds and for isomer separation. Normal phase HPLC requires a polar stationary phase combined with non or ...

The term liquid chromatography (LC) refers to a class of physicochemical methods which are used to separate and quantify compounds in a sample. LC is made up of a liquid mobile phase, which carries ...

In 1964, University of Utah Chemistry Professor J. Calvin Giddings enunciated a theoretical platform that would provide liquid chromatography (LC) with resolving power equivalent to that of gas ...

Chromatographic techniques with chiral cyclodextrins (CDs) anchored onto stationary support materials, known as chiral stationary phases (CSPs), afford a direct and simple approach for enantiomer ...

High-performance liquid chromatography (HPLC) for enantiomeric separation of chiral active pharmaceutical ingredients took the drug industry by storm in the late 1990s. Drug companies needed a ...

Operating HPLC at higher than ambient temperatures can improve peak shapes and enable faster run times. Preheating the mobile phase is significant in high temperature liquid chromatography as the ...

Polysaccharide-based chiral stationary phases have been developed that comprise chiral selectors immobilized on their support rather than being physically coated. These materials are completely ...