A comprehensive map of aberrant hematopoiesis in people with acute myeloid leukemia defines specific cell states and potential therapeutic targets. The team used their reference map for normal ...

Research identifies ribosome biogenesis factor MYBBP1A as a driver of acute myeloid leukaemia growth, highlighting a ...

Lymphoid-derived conventional dendritic cells (L-cDCs) may play a unique function associated with immune suppression and allergy induction, as reported by researchers from Japan. Long thought to arise ...

Researchers identify a mechanism regulating MEF2C stability in acute myeloid leukaemia and demonstrate a peptide strategy that suppresses disease progression.

KAT2A is a histone acetyltransferase that functions as a transcriptional activator which, together with its paralogue KAT2B, is markedly overexpressed in acute myeloid leukemia (AML) compared to in ...

Lung tumors don't just evade the immune system. They reshape it at its source. Researchers from the Icahn School of Medicine at Mount Sinai and collaborators report in the September 10 online issue of ...