Leptin is an adipose tissue hormone that regulates energy and metabolic balance by activating the leptin receptor (LEPR). An imbalance in leptin or LEPR signalling — whether through hyperleptinemia or ...
Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...
Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic ...
Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...
Benjamin Freitag was always hungry as a child, even after meals, and weighed nearly 100 lbs. by the time he was 3 He was eventually diagnosed with a leptin deficiency, which caused his brain to tell ...
Leptin is a hormone that plays a key role in controlling food intake and energy homeostasis. Skeletal muscle is an important target for leptin and recent studies have shown that leptin deficiency may ...
Novelion Therapeutics' (NVLN +1%) European subsidiary files a Marketing Authorization Application (MAA) seeking approval for Orphan Drug-tagged metreleptin as replacement therapy to treat ...
Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic ...
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