Scientists have uncovered a gut-specific epigenetic aging mechanism that links inflammation and iron imbalance to cancer risk ...

Although the gut renews itself constantly, its stem cells accumulate age-related molecular changes that quietly alter how ...

Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in the ...

The study, “A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts,” was published in Immunity. The team, led by Carlene L. Zindl, Ph.D., found that IL-22 ...

Chemical and Biological Engineering PhD student Max Yavitt is the lead author on a new paper in Science Advancesthat focuses on intestinal tissue research. The work could allow researchers to control ...

The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at ...

The human small intestine is an essential organ that helps us absorb nutrients and vitamins from food. It is an average of 6 meters long and is covered with millions of villi that are separated by ...

Pythons may hold the answer to another way to regrow our guts, a group of researchers led by the University of Texas at Arlington finds. In a recent study published in the journal Proceedings of the ...

Colorectal cancers, which kill more than 900,000 people each year, are notoriously heterogeneous. The cell type and the genetic mutations that give rise to the tumors and the effect of the tumor ...

As people live longer, the gut quietly accumulates damage that can tip the balance between healthy tissue renewal and chronic ...