Years before he conducted the research that would earn him a Nobel Prize in Physiology and Medicine, Shinya Yamanaka, MD, ...

An intestinal pathogen reshapes the gut environment to fuel its own colonization and cause diseases, a multi-institutional ...

Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess cells are pushed out.

An intestinal pathogen reshapes the gut environment to fuel its own colonization and cause diseases, a multi-institutional ...

Human organoids are 3D cell cultures derived from adult stem cells and maintain the variable distribution of epithelial cells seen in primary tissue. They can recapitulate the mechanisms of epithelial ...

A recent study comparing young and aged mouse intestinal tissues revealed a delicate balance between IFN-γ signaling and ERK/MAPK signaling as crucial for maintaining the intestinal stem cell ...

The trillions of microbes in our gastrointestinal tract, known as the gut microbiome, are crucial to the body; the gut microbiome aids in digestion, nutrient absorption, and influences our health in ...

A stem cell-derived intestine model reveals glycyrrhizin as a potential treatment for inflammatory bowel disease.

A new study reported in Nature has determined that the amino acid cysteine could promote regeneration among cells in the small intestine. The work showed that cysteine can activate an immune signaling ...

The intestinal immune system can usually recognize friend from foe. But for approximately 30 million Americans with food allergies—including four million children—immune cells mistakenly identify food ...