Altered intestinal barrier function is postulated to be a central predisposing factor to intestinal diseases, including inflammatory bowel diseases and food allergies. However, the mechanisms involved ...

While in vivo animal models are commonly employed for pharmacokinetic studies, they are often expensive, low in throughpu,t and typically fail to accurately replicate key characteristics of the human ...

The terms "intestinal barrier" and "intestinal permeability" describe two different aspects of the same anatomical structure, the intestinal wall composed of four layers, the mucosa, the submucosa, ...

An international research team led by scientists from Bern and Charité - Universitätsmedizin Berlin has identified a previously unknown function of the intestinal nervous system. The study reveals ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how 5S-Heudelotinone alleviates experimental colitis by shaping the immune system and enhancing the intestinal barrier in a gut ...

mTOR, mammalian target of rapamycin; p70S6K, The 70kDa ribosomal S6 kinase 1; NLRP3, NOD-like receptor thermal protein domain associated protein 3; ASC, apoptosis-associated speck-like protein ...

(Beyond Pesticides, March 13, 2025) Study results published in Pesticide Biochemistry and Physiology “suggest that combined [pesticide] exposure may further amplify the toxicity and compromise the ...