In summary, macrophages secrete IFN-β, activating the IFN-β-IFNAR-p-STAT1 axis in MICFs, leading to increased secretion of CCL2/7/12 chemokines and subsequent recruitment of more IFN-β-secreting ...
Sept. 29, 2005 -- Interferon -- a critical protein that mediates the body's defense against a wide variety of infectious agents and tumors -- may soon have greater therapeutic value as the result of a ...
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antagonizes interferon (IFN)-mediated host defenses for infection establishment. SARS-CoV-2 nucleocapsid proteins further enhance its ...
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