ALN1003 demonstrated consistent, favorable effects across key drivers of metabolic disease, including reductions in body weight and fat mass, ...

Restricting access to a high-fat diet (HFD) in mice to either their active or inactive period promoted vastly different effects on their food preference and meal patterns that parallel behaviors ...

Researchers observed treatment-linked improvements in body composition, including lower fat mass and relatively higher lean ...

Obesity now affects nearly half of adults worldwide. Global estimates show about 43 percent of adults are overweight, and 16 percent live with obesity. These numbers matter because excess weight ...

Obesity does not just enlarge fat stores, it appears to rework the body’s wiring and immune landscape in ways scientists have ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

The pleasure we get from eating junk food—the dopamine rush—is often blamed as the cause of overeating and rising obesity rates in our society. But paradoxically, anecdotal evidence suggests that ...