Solution to duplicating the eukaryotic genome 3 billion bps in the human genome. About 50,000 replication origins/genome. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news ...
The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...
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