Researchers at The University of Texas MD Anderson Cancer Center have discovered that an investigational epigenetic therapy ...

Preclinical study results suggest that targeting Hippo signaling may help address treatment resistance in acute myeloid ...

Endocrine resistance—a major cause of breast cancer deaths—can be underpinned by an epigenetic change called DNA methylation, researchers at the Garvan Institute of Medical Research have discovered.

This review is designed by Dr. Yinglan Zhao and written by her PhD students Dr. Lei Tao and Yue Zhou (Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University).

Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical regions of the central nervous system, such as the pons, thalamus, and spinal ...

Blindness itself might become, at least in certain cases, partially reversible. This potential future stems from one of the most intriguing developments in regenerative medicine: epigenetic ...

Epigenetic modulation encompasses reversible alterations to the chromatin landscape that regulate gene expression without changing the underlying DNA sequence. In glioblastoma, a highly aggressive ...

Researchers have revealed a reason why endocrine resistance develops in breast cancers and how to potentially treat it in patients. Endocrine resistance -- a major cause of breast cancer deaths -- can ...

Epigenome remodeling, including widespread changes to DNA methylation and 3D chromatin structure, is increasingly recognized as an important mechanism of gene deregulation in cancer. For example, at ...