Many RNA polymerase II (Pol II)-transcribed genes are regulated at the level of transcription elongation, which has three main stages: promoter escape, promoter-proximal pausing, and productive ...
Transcription through early-elongation checkpoints requires phosphorylation of negative transcription elongation factors (NTEFs) by the cyclin-dependent kinase (CDK) 9. Using CDK9 inhibitors and ...
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