Adults with suspected celiac disease and no immunoglobulin A (IgA) deficiency most likely can avoid a diagnostic bowel biopsy if they have high serum anti-tissue transglutaminase IgA (tTG-IgA).
Our discussion focuses upon predictions and wishes regarding diagnostic aspects of CD, mindful that we also expect significant advances to occur with respect to treatment in the foreseeable future.
Celiac disease is an immune-mediated enteropathy triggered by gluten in genetically predisposed individuals (HLA-DQ2/DQ8), with a global seroprevalence of approximately 1.4%. However, only one in four ...