Macrophages remain ready to fight infection thanks to signaling molecules left behind by previous infections. That is according to new research from scientists at the University of California, Los ...

Scientists in the Blavatnik Institute at Harvard Medical School and MIT have created a new family of tools that, for the first time, illuminates the missing half of how the immune system uses ...

In cancer, particularly at late stages, strong regulatory T-cell (Treg) suppression and dysfunctional cytotoxic T lymphocytes hinder effective antitumor immunity. While anti-OX40 (aOX40) antibodies ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

Cytokines are well-known players in the immune response, helping to control inflammation and coordinate the responses of other immune cells. However, a growing body of evidence suggests that some ...

Psoriasis, a chronic inflammatory skin condition characterized by dry and scaly skin lesions, affects about 7.5 million people in the United States. Psoriasis results from abnormal proliferation of ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...