The polysaccharide β-1,2-glucan consists of repeating units of glucose linked together by β-1,2-glycosidic bonds. Cyclic β-1,2-glucans (CβGs) occur in different bacterial species and have a role in ...

Cyclic tetrapeptides comprise a potent and selective class of molecules with a wide range of biological activities, including the phytotoxic activity of tentoxin and the histone deacetylase (HDAC) ...

Epothilones are thiazole-containing natural products with anticancer activity that are biosynthesized by polyketide synthase (PKS)-nonribosomal peptide synthetase (NRPS) enzymes EpoA–F. A cyclization ...

SOME MARINE organisms have a knack for making steroidal compounds containing halogens. Chemists have long tried to do the same thing, because such compounds can be useful, for example, in treating ...

A catalytic dehydrogenation approach promises to streamline access to products of the ring-forming Diels-Alder reaction. The approach generates starting materials and enables them to be cyclized in a ...