Regulation of nuclear receptor activity is the focus of numerous ongoing studies to develop novel therapies for the treatment of hormone-related cancer. Although cyclin D1 functions to control the ...
Rett syndrome (RTT) is a severe neurological disorder that is caused by mutations in the MECP2 gene. Many missense mutations causing RTT are clustered in the DNA-binding domain of MeCP2, suggesting ...
Jian Xu, Daniel E. Bauer, Marc A. Kerenyi, Thuy D. Vo, Serena Hou, Yu-Jung Hsu, Huilan Yao, Jennifer J. Trowbridge, Gail Mandel, Stuart H. Orkin Proceedings of the National Academy of Sciences of the ...