Circuits in the brain act as an internal clock to tell us it is time to sleep and to control how long we then stay asleep. A new study in flies suggests a part of that clock constantly monitors ...

Most biochemical reactions accelerate as temperature increases, but our daily circadian rhythms, which are underlain by gene regulatory and biochemical networks, remain constant, even as temperatures ...

One important aspect of the internal time-keeping system continues to perplex scientists: its complex response to temperature, which can shift the clock forward or backward, but cannot change its ...

Researchers at UT Southwestern Medical Center have found that fluctuations in internal body temperature regulate the body's circadian rhythm, the 24-hour cycle that controls metabolism, sleep and ...

The Earth’s daily rotation has ensured that the majority of species possess an endogenous timekeeper which controls physical and behavioural changes in a repeating 24-h cycle 9,10. This circadian ...

Systems-biology approaches, such as genetic perturbations combined with kinetic luminescence imaging, synthetic-biology approaches and mathematical modelling, are being used to address the complexity ...

Researchers led by Gen Kurosawa at the RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS) in Japan have used theoretical physics to discover how our biological clock ...