Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...
Study: Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER. Image Credit: Anusorn Nakdee/Shutterstock.com In a recent study published in Nature ...
The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...
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