T-cell redirection therapy using chimeric antigen receptor (CAR) T cells and/or bispecific antibody (BsAb) has been established and become a promising treatment strategy for relapsed/refractory B-cell ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now discovered that CAR molecules can be transferred from the CAR-T cells to ...

Ionising radiation can provoke biological responses not only in directly irradiated cells but also in neighbouring or distant non-irradiated cells, a phenomenon known as the radiation-induced ...

Los Alamos National Laboratory biologist Bruce Lehnert's study of the effects of extracellular mediators, including proteins, from irradiated human cells on non-irradiated cells has confirmed the ...

A CAR-T cell product can contain both CAR-T cells and CAR-negative bystander T cells (left). After treatment with CAR-T cell therapy, CAR-T cells kill tumor cells and release a panel of cytokines. In ...