Mitochondrial diseases (MD) remain an urgent clinical challenge due to the lack of reliable biomarkers and effective therapies. Patients often go undiagnosed until severe tissue failure occurs, and ...

At the onset of diabetic cardiomyopathy, Trdn-as expression increases, which regulates the methylation of Casq2 mRNA mediated by METTL14, thus increasing the stability and expression of Casq2 mRNA.

Type 2 diabetes doesn’t just raise the risk of heart disease—it physically reshapes the heart itself. Researchers studying ...

Scientists have uncovered new evidence showing how type 2 diabetes directly reshapes the human heart, altering both its energy production and physical structure.

Despite being renowned as the “powerhouse of the cell,” mitochondria can also be a source of heartache for those living with mitochondrial disease—especially when planning to have children. Because ...

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Diabetic cardiomyopathy (DCM) is a specific type of cardiomyopathy that is independent of hypertension and ...

The UK's pioneering licensed IVF technique to reduce the risk of mitochondrial diseases carried out in Newcastle has seen eight babies born, research shows. All eight babies show no signs of having ...