Thyroid cancer cells undergo profound metabolic reprogramming to support rapid proliferation, survival under stress and metastatic spread. A hallmark of this reprogramming is the shift from ...

A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer progression, offering fresh perspectives for the ...

An international research team, led by Justus Liebig University Giessen (JLU), the Institute for Lung Health (ILH) in Giessen ...

Osteosarcoma, the most common primary malignant bone tumour in adolescents and young adults, is defined by profound shifts in energy metabolism that support rapid growth, invasion and resistance to ...

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

A unique property of cancer cells is their ability to undergo metabolic reprogramming, during which they preferentially utilize aerobic glycolysis, glutaminolysis, mitochondrial respiration, and other ...

An international research team, led by Justus Liebig University Giessen (JLU), the Institute for Lung Health (ILH) in Giessen, and the Max Planck Institute for Heart and Lung Research in Bad Nauheim, ...

Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, CD8⁺ T-cell exhaustion, EMT, and fibrosis that reinforce immune-protected ...

GLP-1 drugs commonly used for weight loss and diabetes decreased the risk of cancer spreading in patients with several ...

Over the last few decades, physical principles have been proposed to explain some biological processes and functions. However ...

In a recent study, Stevens researchers have shown how colorectal cancers can evolve from mature intestinal cells that revert ...