Biomolecular phase separation is an emerging concept in cell biology that explains how specific proteins and nucleic acids dynamically organise into distinct, membrane‐less compartments. These ...
With an increasingly profound understanding of the interplay between condensate biology and diseases, there is a poised acceleration of classical drug development processes, catalyzing breakthroughs ...
Researchers have identified a new class of RNA molecule, called smOOPs, which support cellular phase separation, where macromolecules form biomolecular condensates that are critical for cell function.
CluMPS—Clusters Magnified by Phase Separation—is a fluorescent reporter strategy for detecting protein clusters. It promises to facilitate the visualization of protein clusters that are too small to ...
If your holiday season activities include a luxury cruise or feasting on raw oysters, then beware: Norovirus, a gastrointestinal RNA virus that can cause nausea and diarrhea, could be an unwelcome ...
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Simple vibration platform enables uniform biomolecular condensate formation
A research group led by Professor Hiroaki SUZUKI and Takeshi HAYAKAWA from the Faculty of Science and Engineering at Chuo University, graduate student Zhitai HUANG, graduate students Kanji KANEKO (at ...
Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...
Two Johns Hopkins assistant professors, chemist Xiongyi Huang and biophysicist Yaojun "Jun" Zhang, have been named 2025 Sloan Research Fellows by the Alfred P. Sloan Foundation. These two-year, ...
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