A new technique, named assay of transposase-accessible chromatin with visualization (ATAC-see), allows imaging and sequencing of the accessible genome in the same cells. Existing epigenome analysis ...

For the investigation the team used a combination of two technologies—CRISPR screening and ATAC-see. While the former is a method to suppress the function of a desired set of genes, the latter is a ...

Before DNA transcription, replication and repair can occur in eukaryotes, chromatin must transition from a tightly packed, condensed state to a more 'open' state. Chen et al. modified a previously ...

KANAZAWA, Japan, Feb. 16, 2024 /PRNewswire/ -- In a study recently published in Nature Genetics, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University explore chromatin ...

Nature Genetics, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University explore chromatin accessibility, i.e., endogenous access pathways to the genomic DNA, and its use as a ...