Focal adhesions are protein assemblies that allow cells to adhere to and interact with their surrounding matrix. DNA repair pathways and other responses to genotoxic stress have been well described, ...

Immunofluorescence image showing S100A11 (green) localization to focal adhesions and actin stress fibers in a HeLa cell. Microtubules are labeled in red. Researchers at Kanazawa University report in ...

Researchers from Tokyo Medical and Dental University (TMDU) identify a novel mechanism by which cells adhere more strongly to their surrounding matrix in response to stress Tokyo, Japan – The DNA ...

The following represents disclosure information provided by the author of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted ...

Overexpression of focal adhesion kinase (FAK) is linked to worse prognosis and greater risk of metastasis in colorectal, cervical, breast and skin cancers. Despite its attractiveness as a therapeutic ...

“Cell migration is required and essential for metazoan development, tissue regeneration and repair, as well as in immune surveillance. Many diseases such as cancer, fibrosis, and inherited ...

For more than two decades, University of Alabama at Birmingham researcher Susan Bellis, Ph.D., has studied how the addition of sialic acid to various proteins increases cancer resistance and ...

Cells in the body have to move around in order to do their jobs. During development, for instance, cells are distributed to create and grow tissue. And in the event of an immune response, different ...